Shingles is a viral infection that makes the skin break out in a painful rash and usually affects older people. It is caused by the same virus that causes chickenpox. Shingles often begins with burning, tingling, itching, or numbness on the skin. After several days, a rash of blisters breaks out in one area or on one side of the body. The blisters may itch, or they may be painful. The blisters may be accompanied by fever, headache, fatigue, and sensitivity to light.