Piriformis injections can help relieve sciatic nerve pain in Lakeland, Florida.

If you are suffering from sciatic nerve pain that runs down your leg like a jolt of lightning and traditional pain relievers haven’t provided relief, a piriformis injection might be worth exploring. This targeted injection aims to soothe the piriformis muscle, which can sometimes be the culprit behind sciatica pain. We investigate the piriformis injection and whether it might be right for you.

In This Article:

Piriformis Muscle

The piriformis muscle is a band of muscle tissue that stretches from the lower spine to the upper surface of the femur. When the piriformis muscle irritates or compresses the nearby sciatic nerve, it can cause a range of symptoms, from a dull ache to a sharp, shooting pain in the buttock area.

The pain can extend down the leg, following the sciatic nerve and mimicking sciatica. Any activity involving the hip, particularly those that require turning or lifting the leg, engages the piriformis muscle.

Piriformis Injection into the Piriformis Muscle

A piriformis injection delivers a potent combination of a steroid and anesthetic medication directly into the piriformis muscle. The steroid, often a corticosteroid, is designed to reduce inflammation and calm the irritated muscle, easing pressure on the sciatic nerve. The anesthetic medication brings not just immediate but also prolonged relief from the pain while the steroid goes to work.

The goal of the injection is to break the muscle spasms and nerve compression so that the patient can move, sit, and sleep without pain. Because it’s an injection, the medication is administered directly to the source of the pain and often achieves quicker and more focused results than oral medications.

How Do Injections Target Piriformis Discomfort?

When administered, the injection bathes the piriformis muscle in a soothing combination of a steroid and a powerful anesthetic. This combination reduces the muscle’s inflammation and lessens the spasms, providing relief that can feel almost miraculous if the patient has suffered from the discomfort for a long time.

The process isn’t just about relief, though. By calming the muscle and reducing the swelling, these injections also alleviate the pressure on the sciatic nerve that typically generates shooting pains down the leg. Addressing both the muscle and the nerve makes it possible to return to your usual activities sooner rather than later.

Post-Injection Care and Results

Following the piriformis injection, patience is vital. The body requires time to heal and respond to the treatment. Initially, pain levels may change due to the anesthetic; however, the steroid’s long-term relief should kick in after a few days when you can return to normal activities.

To optimize recovery, your pain doctor might recommend specific exercises to stretch and strengthen the piriformis muscle and surrounding areas. Physical therapy can also significantly affect your long-term treatment plan, providing structured guidance to keep your muscles loose and limber.

Actively participating in your recovery through recommended lifestyle changes, like adjusting your posture or exercise regimen, can also significantly contribute to managing symptoms and helping prevent future flare-ups.

With a blend of medical treatment, self-care, and possible follow-up injections for ongoing management, the goal is a more comfortable, active life without piriformis-induced pain.

Temporary Side Effects

Following the injection, possible local reactions like swelling, redness, or bruising at the injection site may occur, which generally subside within a few days. Rest and ice packs are usually sufficient to manage them. Some patients encounter a bit of dizziness, nausea, or even some sweating. There is also the possibility of a temporary increase in pain, too. The patient may temporarily experience muscle spasms.

The side effects are typically short-lived, and oral pain medications can bridge the gap until the steroid’s full calming effects take effect.


What conditions are treated with piriformis injections?

Piriformis injections primarily treat the discomfort associated with piriformis syndrome, where the piriformis muscle irritates the sciatic nerve. They’re also used to diagnose and manage sciatica symptoms mainly from the buttocks rather than the lower back, offering pain relief and functional improvement.

How quickly will I get relief?

You may begin to feel relief from a piriformis injection within 3 to 7 days following the procedure. However, every individual’s response can vary based on their unique condition and overall health.

How long does a piriformis injection last?

Relief from a piriformis injection can last from a few weeks to several months. Its longevity depends on individual factors like the severity of symptoms and response to the steroid medication. It is important to have realistic expectations and discuss potential outcomes with your pain doctor.

Are you sedated for piriformis injection?

Sedation for a piriformis injection is generally not necessary; the procedure typically uses local anesthetic. However, your doctor may suggest mild sedation if you’re particularly anxious. Discuss your options and concerns with your doctor.

What should I avoid after receiving an injection?

After receiving a piriformis injection, your doctor may want you to avoid driving for the rest of the day and refrain from soaking in water, like baths, pools, or hot tubs, for 24 hours. You’ll typically also wait three days before resuming physical therapy or any rigorous physical activity to allow the treatment to settle in.

How often can I get piriformis injections for chronic pain?

For chronic pain, piriformis injections are typically spaced out, often several months apart. Most medical guidelines suggest limiting injections to a few times a year to reduce potential side effects from steroids. Your pain doctor will determine the best frequency based on your response to treatment and overall health.

What happens if the piriformis injection doesn’t work?

If a piriformis injection doesn’t alleviate your pain, it could indicate other causes for your symptoms or that your condition is less responsive to steroids. Your pain doctor may reassess your situation and recommend alternative therapies, additional diagnostic tests, or consider other injection sites or types of injections to manage your pain better.


If you’ve been experiencing pain caused by piriformis syndrome or sciatica-like symptoms, piriformis injections offer the prospect of potential relief. However, everyone responds differently to the injection, and what works for one may not work for another. While these injections offer hope for many, having realistic expectations and being mindful of aftercare and long-term health practices for optimum results is essential.

An open dialogue with your doctor can help you choose the proper treatment, understand potential risks, and explore further options if needed. The road to recovery might not be instant, but with the right approach and care, a piriformis injection could be a step in regaining a pain-free and mobile life.

Novus Spine & Pain Center

Novus Spine & Pain Center is in Lakeland, Florida, and treats patients with chronic pain with numerous therapies, including piriformis injections. By using a comprehensive approach and cutting-edge therapies, we work together with patients to restore function and regain an active lifestyle while minimizing the need for opiates.

For your convenience, you may schedule an appointment online, request a call back, or call our office at 863-583-4445.


Piriformis Injection (PubMed)
Piriformis Syndrome Injections (Columbia University Irving Medical Center)
Piriformis Injection (UCI Health)
Piriformis Muscle Injections (Baker Valley Physical Therapy)
Piriformis Steroid Injection (Mary Greeley Medical Center)
Piriformis Injection: An Ultrasound-Guided Technique (PubMed)
Piriformis Injection (Medscape)
Piriformis Muscle Injections (Melbourne Radiology Clinic)
Piriformis Injection (Mass General Brigham)
Piriformis Muscle Injection (Advanced Orthopaedics & Sports Medicine)